SPRAVATO® / ESKETAMINE TREATMENT CENTER

At Orion TMS, we understand that every individual's mental health journey is unique, and we proudly commit ourselves to offering innovative solutions to empower you on your path to mental wellbeing. One such treatment we offer is esketamine—a breakthrough therapy transforming lives.

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WHAT IS ESKETAMINE?

Esketamine is an FDA-approved medication for its rapid and effective relief of treatment-resistant depression and other mood disorders. Derived from ketamine, esketamine is administered via nasal spray, making it convenient and non-invasive. It shows promising results in helping those who have not responded to traditional antidepressants.

Is Spravato® Right For You?

If you have been struggling with persistent depressive symptoms despite trying various treatments, esketamine or Spravato® nasal spray may be a viable option for you. Our dedicated team of mental health professionals will conduct a thorough evaluation to determine if esketamine aligns with your unique needs and treatment goals.

Esketamine nasal spray is FDA-approved for people with depression who have not experienced improvement after trying at least two different medications. You must currently be taking an antidepressant in order to receive esketamine and you should not take the nasal spray if you have uncontrolled hypertension, a history of strokes or brain bleeds, or abnormal blood vessels at risk of bleeding.

Eskatamine works by isolating the effective part of ketamine. It removes the sedating part which is not believed to be useful for treating depression. Esketamine is a psychedelic-like treatment for depression. Therefore, you may feel dizzy, euphoric, or intoxicated during treatment. Throughout your treatment, our team will be on-site to assist you.

GET HELP WITH DEPRESSION! IT'S IMPORTANT TO KNOW THAT YOU ARE NOT ALONE.
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woman happy from spravato treatment in northbrook Illinois
TMS THERAPY & ESKETAMINE CAN HELP WITH:
  • Depression
  • Sadness or Despair
  • Low Mood or Lethargy
  • Irritability
  • Lack of Joy
  • Social Isolation
  • Self-Harm
  • Eating Disorders
  • Substance Abuse
  • Drug & Alcohol Addiction

Discover hope and relief with Spravato®, an FDA-approved breakthrough for depression treatment. 

After treatment, you may experience grogginess and dizziness, so avoiding hazardous activities, including driving, is important. Arrange for someone to accompany you and drive you home after your session. We also recommend scheduling treatments in the afternoon so you can return home, have dinner, and go to sleep. By morning, most people can resume daily activities.


If you’ve struggled with treatment-resistant depression (TRD), undergoing esketamine treatment can transform your life.

Relief can happen rapidly.


Esketamine nasal spray acts rapidly by enhancing NMDA receptors in the brain, promoting neurotransmitter release and synaptic connections. This mechanism swiftly adjusts neural communication, making it effective for treatment-resistant conditions.


Nasal administration ensures quick absorption and distribution, providing prompt relief to individuals in need.

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LEARN MORE ABOUT ESKETAMINE

Esketamine has shown remarkable efficacy in rapidly alleviating depressive symptoms, offering hope to individuals facing treatment-resistant depression. The treatment is administered in our comfortable and secure environment, under the supervision of our experienced mental health professionals.

As per FDA guidelines, you can only receive esketamine treatment "under the supervision of a healthcare provider in an authorized doctor's office or clinic." Therefore, our team will closely monitor your administration, observe your vital signs, and assess your clinical condition. Your blood pressure will be checked before treatment, 40 minutes in, and before you leave.

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YOU'VE GOT QUESTIONS, WE'VE GOT ANSWERS.

Many people who are curious about Esketamine as a treatment option often ask the same questions. Please review our frequently asked questions or feel free to call us for more information:   (224) 955-7828

  • How long it takes and what to expect?

    Esketamine nasal spray treatment typically requires 24-26 sessions divided into four phases:


    Phase 1: Two treatments per week for four weeks.

    Phase 2: One treatment per week for four weeks.

    Phase 3: One treatment every 1-2 weeks.

    Phase 4: Maintenance program with 12-14 additional treatments.


    Before each appointment, avoid eating for two hours and limit fluid intake for 30 minutes. Our team will help you self-administer the nasal spray while seated, and blood pressure is checked at the start, 40 minutes in, and before leaving. Plan to stay at the center for at least two hours and have someone there to drive you home.


  • What are the side effects of Esketamine?

    During esketamine treatment, individuals may encounter mild to severe side effects. These commonly reported effects include dizziness, nausea, vomiting, sleepiness, vertigo, and dissociation. Patients also report constipation, diarrhea, dry mouth, fatigue, headache, nose or throat discomfort, and numbness around the nose and mouth. 


    Most of these side effects are typically temporary and manageable. If you experience persistent or bothersome symptoms, consult our team and we will help you manage them. 


  • Does insurance cover Esketamine?

    Most major insurance providers include coverage for ketamine-based depression treatment if you have not experienced improvement after attempting two antidepressants. Typically, insurance plans cover approximately 28 treatment sessions.

  • Do I need to have insurance to get Esketamine?

    You do not need to have insurance to receive esketamine treatment, and we offer self-pay rates. Please contact us for more information.

  • Do you take over all my psychiatric and/or medical care?

    We only provide the esketamine treatment and the necessary evaluations related to this. It is important that any other doctors working with you during our treatments communicate any medication changes.